Paraoxonase-1 by Inflammation in Murine Hepatocytes Reciprocal and Coordinate Regulation of Serum Amyloid A Versus Apolipoprotein A-I
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چکیده
Chang Yeop Han, Tsuyoshi Chiba, Jean S. Campbell, Nelson Fausto, Michelle Chaisson, and Paraoxonase-1 by Inflammation in Murine Hepatocytes Reciprocal and Coordinate Regulation of Serum Amyloid A Versus Apolipoprotein A-I Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2006 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the American Heart Association, 7272 Arteriosclerosis, Thrombosis, and Vascular Biology doi: 10.1161/01.ATV.0000227472.70734.ad 2006;26:1806-1813; originally published online May 18, 2006; Arterioscler Thromb Vasc Biol. http://atvb.ahajournals.org/content/26/8/1806 World Wide Web at: The online version of this article, along with updated information and services, is located on the http://atvb.ahajournals.org/content/suppl/2006/05/21/01.ATV.0000227472.70734.ad.DC1.html Data Supplement (unedited) at:
منابع مشابه
Reciprocal and coordinate regulation of serum amyloid A versus apolipoprotein A-I and paraoxonase-1 by inflammation in murine hepatocytes.
OBJECTIVE During inflammation, the serum amyloid A (SAA) content of HDL increases, whereas apolipoprotein A-I (apoA-I) and paraoxonase-1 (PON-1) decrease. It remains unclear whether SAA physically displaces apoA-I or if these changes derive from coordinated but inverse transcriptional regulation of the HDL apolipoprotein genes. Because cytokines stimulate the hepatic expression of inflammatory ...
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